IMBRAVE 151: A RANDOMIZED PHASE II TRIAL OF ATEZOLIZUMAB COMBINED WITH BEVACIZUMAB AND CHEMOTHERAPY IN PATIENTS WITH ADVANCED BILIARY TRACT CANCER

IMbrave 151: a randomized phase II trial of atezolizumab combined with bevacizumab and chemotherapy in patients with advanced biliary tract cancer

Background: Biliary tract cancers (BTCs) are heterogenous, highly aggressive tumors that harbor a dismal prognosis for which more effective treatments are needed.The role of cancer immunotherapy in BTC remains to be characterized.The tumor microenvironment (TME) of BTC is highly immunosuppressed and combination treatments are needed to promote effe

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Improved Mixed-Integer Linear Programming Model for Short-Term Scheduling of the Pressing Process in Multi-Layer Printed Circuit Board Manufacturing

The pressing process is a part of the fabrication process of multi-layer printed circuit board (PCB) manufacturing.This paper presents the application of a new mixed-integer linear programming model to Figure Skating - Clothing - Adult Dresses the short-term scheduling of the pressing process.The objective was to minimize the makespan.The proposed

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Adoption of Green Industrial Internet of Things to Improve Organizational Performance: The Role of Institutional Isomorphism and Green Innovation Practices

Emerging technology developments Rocking Chair and functions of the Internet of Things (IoT) in industrial systems are leading the development of the Industrial IoT (IIoT).Greener, i.e., cleaner environmental goals can be achieved by putting green IIoT (GIIoT) into practice.This research aims to explore the reasons for the adoption of GIIoT in orga

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Spatial tools for diagnosing the degree of safety and liveability, and to regenerate urban areas in the Netherlands

This contribution describes the tool Social Safe Urban Roper Style Saddle Design (SSUD), seen together with socio-spatial and linguistic challenges when applying space syntax in the regenerating of problem urban areas.The Space Syntax jargon is technical and needs to be translated into a language understandable and acceptable to stakeholders who ar

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